Preclinical and Comparative clinical trial of Thetran Ilagam (Internal) and Yogam Therapy in the management of Aan Maladu (Male Infertility)

Karthik Nagarajan, S (2018) Preclinical and Comparative clinical trial of Thetran Ilagam (Internal) and Yogam Therapy in the management of Aan Maladu (Male Infertility). Masters thesis, National Institute of Siddha, Chennai.

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Abstract

The aim of the study is to increase the sperm count and sperm motility in male infertility patient. The trial medicine Thetran Ilagam was prepared as per literature. The duration of the trial period is 45 days. The trial doseisThetran Ilagam 5gm.twice a day withcow's milk.40 patients for the trial based on Inclusion and Exclusion criteria. Before treatment routine blood, urine and semen analysis taken in all 40 patients. This study has been approved by IEC of NIS [Date of IEC Approval & its number: NIS/IEC/2016/11-13/14.10.2016. All 40 cases (20Group I & 20Group II) were treated in OPD of Ayothidoss Pandithar Hospital of National Institute of Siddha, Chennai-47. Patients were instructed to come for next review once in 7 days. 35 patients were come with clinical symptoms like premature ejaculation, erectile dysfunction, and nocturnal emission. The entire details of the patients were noted in the case sheet proforma.The detailed trial of Aan Maladu with reference to its aetiology, pathogenesis, investigations, clinical features, diagnosis and treatment with trial drugs was done. The results were observed by Semen Analysis and Sexual Health Score. All the 40 patients among the 23(57.5%) cases were good improvement, 9(22.5 %) cases were moderate improvement, and 8 (20%) patients were poor improvement. CONCLUSION: The polyherbal formulation Thetran Ilagam exhibited no toxicity on short form administration. The quantitative outcome of Semen Analysis and Sexual Health score shows there is significant improved between at the start and end of treatment i.e the mean and standard deviation is from 13.2±7.14 and 46.8 ± 23.2. The qualitative outcome shows encouraging results of All the 40 patients among the 23(57.5%) cases were good inmprovement, 9(22.5%) cases were moderate improvement, and 8 (20%) patients were poor improvement.From the above results, the trail drugs “Thetran Ilagam” (Internal Medicine) is responded well for the treatment of Aan Maladu. Therefore the author concluded that the yogam based intervention in the management of Aan Maladu produced better outcome.

Item Type: Thesis (Masters)
Additional Information: (Reg.No.321513202)
Uncontrolled Keywords: Thetran Ilagam ; Yogam Therapy ; Aan Maladu ; Male Infertility ; Preclinical and Comparative clinical trial.
Subjects: AYUSH > Sirappu Maruthuvam
Depositing User: Subramani R
Date Deposited: 29 Dec 2018 11:13
Last Modified: 29 Dec 2018 11:13
URI: http://repository-tnmgrmu.ac.in/id/eprint/10255

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