Comparative Clinical Study on Parangisakkai Chooranam (Internal) and Karappan Ennai (External) for the treatment of Karappan (Eczema) with and without Yogam

Dinesh, B R (2018) Comparative Clinical Study on Parangisakkai Chooranam (Internal) and Karappan Ennai (External) for the treatment of Karappan (Eczema) with and without Yogam. Masters thesis, National Institute of Siddha, Chennai.


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The disease Karappan was taken for the clinical study with Parangichakkai chooranam internal medicine and Karappan ennai external application after scrutinized by the Screening committee of National Institute of Siddha. The Clinical study was carried out after obtaining proper permission from IEC of National Institute of Siddha (IEC number: NIS/IEC/2016/11-14/14.10.2016) and the trial was registered in Clinical trial registry of India with the reference number of REF/2018/03/018797.The medicines were prepared after obtaining proper authentication. Biochemical analysis of drugs were performed. Hence the study is safely executed on human volunteer patients. 40 patients were treated in Ayothidoss Pandithar Hospital of National Institute of Siddha. The patients with Karappan were recruited based on Inclusion and Exclusion criteria and detailed study was done. Separate proforma was maintained for each patient along with daily progress chart to monitor the prognosis. CONCLUSION: The clinical trial proves the efficacy of the trial drugs by reducing the clinical signs and symptoms like Itching, Oozing and hyperpigmentation, etc., and provides better cure. The study results shows that 12.5% of them (5 patient) had no reduction in the score, 10% of (4 patients) had mild improvement, 27.5% of (11 patients) had moderate improvement, 50% of (20 patients) had good improvement. Thus these results revealed good relief from the disease after treatment. The trial medicines were prepared from easily available ingredients and the palatability of medicine is better and the dosage is also convenient. Yogam treatment along with internal and external medication shows good results in patients. When these affected individuals get a better management with this trial drug and Yogam, it would be a great benefit for the society. In the present study there was no adverse effect were reported in clinical trial. Hence the drugs were proven for their safety. The Clinical trial conducted in selected patients was satisfactory and encouraging. Further studies may be taken up to establish the efficacy of the drug.

Item Type: Thesis (Masters)
Additional Information: (Reg.No.321513201)
Uncontrolled Keywords: Parangisakkai Chooranam ; Karappan Ennai ; treatment ; Karappan ; Eczema ; with and without Yogam.
Subjects: AYUSH > Sirappu Maruthuvam
Depositing User: Subramani R
Date Deposited: 29 Dec 2018 11:14
Last Modified: 29 Dec 2018 11:14

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