Standardization and Pharmacological Screening of Gandhaga Sarkkarai

Arunkumar, G (2018) Standardization and Pharmacological Screening of Gandhaga Sarkkarai. Masters thesis, National Institute of Siddha, Chennai.


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The test drug Gandhaga Sarkkarai was selected from the Siddha literature Anuboga Vaithiya Navaneetham to evaluate the Anti-histamine, Anti-inflammatory and Analgesic activities. • The dissertation started with an introduction explaining about the Siddha concept, prevalence of Syphilis and role of the test drug in treating Syphilis. • All the ingredients were identified and authenticated by the experts and were purified and the medicine was prepared as mentioned in the Siddha literature. • Review of literature in various categories were carried out. Siddha aspect, botanical aspect, mineralogical aspect and disclosed about the ingredients of the drug and strongly supported that it possesses Anti-histamine, Anti-inflammatory and Analgesic activities. • The drug was subjected to qualitative analysis such as physicochemical, phytochemical, bio-chemical analysis. Quantitatively with FTIR, ICP-OES, HR-SEM with EDAX , HPTLC and TGA analysis which provided the key ingredients present in the drug thus it accounts the efficacy of the drug. • Pharmacological studies revealed that the drug Gandhaga sarkkarai exhibited significant Anti-histamine, Anti-inflammatory and Analgesic activity in animal models. • Results and discussion gives the necessary justifications to prove the potency of the drug. • Conclusion gives a compiled form of the study and explains the synergistic effect of all the key ingredients and activities that supports the study.

Item Type: Thesis (Masters)
Additional Information: (Reg.No.321512202
Uncontrolled Keywords: Standardization ; Pharmacological Screening ; Gandhaga Sarkkarai.
Subjects: AYUSH > Gunapadam
Depositing User: Subramani R
Date Deposited: 29 Dec 2018 13:33
Last Modified: 29 Dec 2018 13:33

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