Arul Priya, S (2018) An Open Non-Randomized Clinical Trial of Kalladaippu Chooranam in Vatha Kalladaippu (Urolithiasis). Masters thesis, Government Siddha Medical College, Chennai.
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Abstract
The clinical study on VATHA KALLADAIPPU was carried out in post graduate department of pothumaruthuvam, Govt. Siddha Medical College, Aringar Anna Hospital, Chennai 106. During the period of 2015-2018. A total of 40 patients was treated in the out patient department. The clinical and pathological assessment was carried out on the basis of Siddha and Modern aspects.All the patients were treated with KALLADAIPPU CHOORANAM with Honey 1g b.d, daily after food for duration of 48 days. • I like to summarize this study with the following highlights. • Males are more prone to get kalladaippu than females according to my studies, males were affected with 60%. • In age distribution, age groups between 31-40 yrs of people are more affected which is 35%. • Office workers (32.5%) and House wives (27.5%) occupy the first two places in occupational classification. • Most of the patient had mixed diet (75%). • Higher incidences of cases were noted in Pinpanikalam (Mid Feb – Mid Apr) which is 57.5%. • Most of the patients were from Neithalthinai (100%). • In Vali, Abanan (100%), Viyanan (100%), Uthanan (25%), Samanan (100%), Koorman (10%), Kirukaran (27.5%), Devathathan (30%) was affected. • In Azhal, Analagam (27.5%), Ranjagam (20%), Saathagam (100%), Alosagam (10%) was affected. • In Iyyam, Avalambagam (100%), Kelathagam (27.5%), Santhigam (32.5%) was affected. • In the disturbance of Ezhu udal thathukkal, 100% saaram, 20% senneer, 32.5% Oon, 32.5% enbu and Moolai 25% were affected. • In Envagaithervu, 5% Naa, 20% Niram, 25% Mozhi, 12.5% Vizhi, 12.5% Sparisam, 7.5% Malam, 87.5% Moothiram were affected. • In Naadi, most of the patients having vali azhal naadi (65%). • In Neikuri examination 65% were having vatha neer. • Among the patients, 100% had flank pain, 50% had burning Micturition, 5% had nausea, 12.5% had fever, Vomiting 25%, Oliguria 30% and 5% had Dysuria. • Most of the patients had stone in both sides of the kidney (45%). • The Toxicological studies of the trial medicine reveal no toxicity. • The pharmacological studies reveal that, the TRIAL MEDICINE has LITHOTRIPTIC ACTIVITY. • Bio-statistical analysis of the clinical trial reveals significant p value <0.05, <0.01 and concludes that the treatment is effective and significant. • After treatment with this trial medicine, most of the symptoms like loin pain, burning Micturition and Dysuria are relieved. The trial medicine shows 32.5% good result and 52.5% moderate result. CONCLUSION: Kalladaippu is a common disorder due to dearrangement of pitha kutram. The dearranged pitham is settled down by the trial medicine by its thuvarpu suvai, on Oppurai Maruthuvam. • Most of the cases noted in Pinpanikalam and munpanikalam in my clinical trial. So, people should take all preventive measures during this period and take enough water. • The Kalladaippu chooranam no toxicity in the preclinical studies and hence proved to be safe for human administration. • Pharmacological study reveals that the trial medicines possess lithotriptic activity. • During clinical trial, no adverse reactions or complications were observed. • The cast of the TRIAL MEDICINE is less also the palatability is alsoacceptable for consume by the patients. • The trial medicine Kalladaippu chooranam showed good results with relieving symptoms in almost 85% patients. • Once again Siddha medicine proves itself as a great boon to mankind.
| Item Type: | Thesis (Masters) |
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| Additional Information: | (Reg.No.321511101) |
| Uncontrolled Keywords: | Kalladaippu Chooranam ; Vatha Kalladaippu ; Urolithiasis ; Open Non-Randomized Clinical Trial. |
| Subjects: | AYUSH > Maruthuvam |
| Depositing User: | Subramani R |
| Date Deposited: | 29 Dec 2018 13:57 |
| Last Modified: | 29 Dec 2018 13:57 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/10219 |
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