A Prospective Open Labelled Randomized Clinical Trial of Seenthil Sarkkarai for Iya Neerizhivu (Chronic Obstructive Pulmonary Disease in Type II Diabetes Mellitus)

Sarangapany, Uthayanan (2018) A Prospective Open Labelled Randomized Clinical Trial of Seenthil Sarkkarai for Iya Neerizhivu (Chronic Obstructive Pulmonary Disease in Type II Diabetes Mellitus). Masters thesis, Government Siddha Medical College, Palayamkottai.


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BACKGROUND: Iya neerizhivu is one of the types of the Madhumega Noikal. It’s maybe correlated with Chronic Obstructive Pulmonary Disease in Diabetes Mellitus. Chronic Obstructive Pulmonary Disease (COPD) is the leading cause of morbidity and mor-tality worldwide. There is evidence to support a connection between COPD and Diabetes mellitus (DM), another common medical disorder. However, additional research is required to improve our knowledge of these relationships and their possible implications. In this study, we investigated the impact of DM on patient outcomes through the clinical course of COPD treated with Seenthil Sarkkarai. METHODS: We conducted a prospective open labelled randomized clinical study in patients from the OPD and IPD of Pothu Maruthuvam Department, GSMCH, Palayamkottai Database between April 2016 and June 2018. 40 Patients with Iya neerizhivu were recruited for evaluated the role of Seenthil Sarkkarai in COPD in type II diabetes. The treatments chedule was 30mg/kg body weight for two times per day with ghee for 90 days. Assessed the FBS, PFT changes, MMRC score, and Lipid Profile before and after treatment. RESULTS: In clinical study 60% of out patients and 55% of In patients showed good improvement 30% of out patients and in 40% of In patients showed Moderate improvement 10% of out patients and 5% of the In patients showed Poor improvement. No adverse reaction was found in this clinical study. The Statistical analysis was done by SPSS statistical package version 20.0. Paired 2 tailed test revealed that the fasting (P < 0.001) and postprandial blood glucose (< 0.001) and HbA1c (P < 0.001), PFT (p < 0.001), showed significant reduction after Seenthil Sarkkarai intervention. The trial drug subjected to biochemical and pharmacological studies and gave significant results also. The results suggest Seenthil Sarkkarai to be beneficial for the treatment of Iya neerizhivu (chronic obstructive pulmonary disease in type II diabetes). Further follow-up studies are warranted to confirm the safety aspects of Seenthil Sarkkarai use.

Item Type: Thesis (Masters)
Additional Information: (Reg. No.321511006)
Uncontrolled Keywords: Seenthil Sarkkarai ; Iya Neerizhivu ; Chronic Obstructive Pulmonary Disease ; Type II Diabetes Mellitus ; Prospective Open Labelled Randomized Clinical Trial.
Subjects: AYUSH > Maruthuvam
Depositing User: Subramani R
Date Deposited: 29 Dec 2018 13:58
Last Modified: 29 Dec 2018 13:59
URI: http://repository-tnmgrmu.ac.in/id/eprint/10218

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